醫學院 - 全職教學人員

于希

助理教授

辦公室：擎天匯校區 PP-R207d

電子信箱： xyu@must.edu.mo

于希博士現任澳門科技大學醫學院助理教授，學生事務處委員。她博士畢業於新加坡國立大學化學學院食品科技系（2019年度最優秀博士畢業生獎），目前主要從事納米材料、分離分析化學以及食品與營養科學領域的研究，至今已發表六十余篇論文在各類行業頂級期刊上，包括Trends in Food Science & Technology, Comprehensive Reviews in Food Science and Food Safety, Analytical Chemistry，Analytical Chemistry，Journal of Agricultural and Food Chemistry，Food Chemistry等，谷歌學術H指數為21。她現任Food and Heath以及《食品研究與開發》青年編委，是包括Journal of Agricultural and Food Chemistry，Food Chemistry等多家學術期刊的專業審稿人。她的工作曾被多家專業媒體報導，包括亞洲最具影響力的英語媒體之一the Strait Times，八頻道新聞等。她的研究曾獲世界上最大的食品和糧油公司之一豐益國際的Arowana營養與安全基金資助，並獲得澳門科技發展基金、四川省國際科技創新合作項目、珠海市產學研合作項目等多項資助。

學歷

PhD National University of Singapore; MSc Jilin University; BSc Jilin University.

教學領域

Fundamental chemistry; Organic chemistry; Analytical chemistry; Biochemistry; Introduction to nutrition science; Mysterious materials.

研究領域

Food safety and nutritional sciences; Nanotechnoloy; Separation science; Analytical chemistry; Public Health.

工作經歷

2019-now assistant professor, Macau Univeristy of Science and Technology;

2018-2019 research fellow, Nanyang Technological University;

2013-2014 research assistant, Dalian Institute of Chemistry and Physics.

學術出版物（精選）

1. He, G.; Chen, X.; Hou, X.; Yu, X.; Han, M.; Qiu, S.; Li, Y.; Qin, S.; Wang, F., UPLC-Q-TOF/MS-based metabolomic analysis reveals the effects of asomate on the citrus fruit. Current Research in Food Science 2023, 6, 100523.

2. Zhao, X.; Wang, A.; Zhai, L.; Gao, J.; Lyu, S.; Jiang, Y.; Zhong, T.; Xiao, Y.; Yu, X., Magnetic solid phase extraction coupled to HPLC-UV for highly sensitive analysis of mono-hydroxy polycyclic aromatic hydrocarbons in urine. Analytica Chimica Acta 2024, 1285, 342020.

3. Zhao, X.; Feng, X.; Chen, J.; Zhang, L.; Zhai, L.; Lv, S.; Ye, Y.; Chen, Y.; Zhong, T.; Yu, X.; Xiao, Y., Rapid and Sensitive Detection of Polycyclic Aromatic Hydrocarbons in Tea Leaves Using Magnetic Approach. Foods 2023, 12 (11), 2270.

4. Zhao, X.; Gao, J.; Zhai, L.; Yu, X.; Xiao, Y. Recent Evidence on Polycyclic Aromatic Hydrocarbon Exposure Healthcare [Online], 2023.

5. Lu, Y.; Li, Z.; Chen, Q.; Fan, Y.; Wang, J.; Ye, Y.; Chen, Y.; Zhong, T.; Wang, L.; Xiao, Y.; Zhang, D.; Yu, X., Association of working hours and cumulative fatigue among Chinese primary health care professionals. Frontiers in Public Health 2023, 11.

6. Zhang, Y.; Qiu, J.; Yang, K.; Lu, Y.; Xu, Z.; Yang, H.; Xu, Y.; Wang, L.; Lin,

Y.; Tong, X.; He, J.; Xiao, Y.; Sun, X.; Huang, R.; Yu, X.; Zhong, T., Generation, mechanisms, kinetics, and effects of gaseous chlorine dioxide in food preservation. Comprehensive Reviews in Food Science and Food Safety 2023, 22 (4), 3105-3129.

7. Wang, A.; Feng, X.; He, G.; Xiao, Y.; Zhong, T.; Yu, X., Recent advances in digital microfluidic chips for food safety analysis: Preparation, mechanism and application. Trends in Food Science & Technology 2023, 134, 136-148.

8. Fu, C.; Guo, H.; You, C.; Yu, X., Recent Advances and Product Opportunities in the Technology of Proteins, Probiotics and Prebiotics. 2023.

9. Yu, X.; Zuo, T., Editorial: Food Additives, Cooking and Processing: Impact on the Microbiome. Frontiers in Nutrition 2021, 8.

10. Ahmad, T.; Nie, C.; Cao, C.; Xiao, Y.; Yu, X.; Liu, Y., First record of Alternaria tenuissima causing Aloe barbadensis leaf blight and leaf spot disease in Beijing, China. Crop Protection 2024, 175, 106447.

11. Cen, K.; Huang, C.; Yu, X.; Gao, C.; Yang, Y.; Tang, X.; Feng, X., Quinoa protein Pickering emulsion: A promising cryoprotectant to enhance the

freeze-thaw stability of fish myofibril gels. Food Chemistry 2023, 407, 135139.

12. He, G.; Hou, X.; Han, M.; Qiu, S.; Yu, X.; Qin, S.; Wang, F.; Li, Y.,Determination of multiclass contaminants in chilli powder based on magnetic multiwalled carbon nanotubes and UPLC-QTOF/MS. Food Research International 2023, 173, 113263.

13. Feng, X.; Cen, K.; Yu, X.; Huang, C.; Yang, W.; Yang, Y.; Tang, X., Quinoa protein Pickering emulsion improves the freeze-thaw stability of myofibrillar protein gel: Maintaining protein composition, structure, conformation and digestibility and slowing down protein oxidation. International Journal of Biological Macromolecules 2023, 253, 126682.

14. Jiang, T.; Dong, Y.; Zhu, W.; Wu, T.; Chen, L.; Cao, Y.; Yu, X.; Peng, Y.; Wang, L.; Xiao, Y.; Zhong, T., Underlying mechanisms and molecular targets of genistein in the management of type 2 diabetes mellitus and related complications. Critical Reviews in Food Science and Nutrition 2023, 1-13.

15. Feng, X.; Yu, X.; Yang, Y.; Tang, X., Improving the freeze-thaw stability of fish myofibrils and myofibrillar protein gels: Current methods and future perspectives. Food Hydrocolloids 2023, 144, 109041.

16. Wu, T.; Zhu, W.; Chen, L.; Jiang, T.; Dong, Y.; Wang, L.; Tong, X.; Zhou, H.; Yu, X.; Peng, Y.; Wang, L.; Xiao, Y.; Zhong, T., A review of natural plant extracts in beverages: Extraction process, nutritional function, and safety evaluation. Food Research International 2023, 172, 113185.

17. Chen, S.; Feng, X.; Yu, X., Editorial: Advances on innovative

protein-based complexes with promising functionality, nutrient retention and encapsulation capacity. Frontiers in Nutrition 2023, 10.

18. Jiang, D.; Yu, X.; Zhong, T.; Xiao, Y.; Wang, L., The Situation and Influencing Factors of Depression and Anxiety in Patients of Hemodialysis during the COVID-19 Pandemic in China. Healthcare 2023, 11 (7), 941.

19. Ahmad, T.; Xing, F.; Nie, C.; Cao, C.; Xiao, Y.; Yu, X.; Moosa, A.; Liu, Y., Biocontrol potential of lipopeptides produced by the novel Bacillus subtilis strain Y17B against postharvest Alternaria fruit rot of cherry. Frontiers in Microbiology 2023, 14.

20. Wolfe, W.; Xiang, Z.; Yu, X.; Li, P.; Chen, H.; Yao, M.; Fei, Y.; Huang, Y.; Yin, Y.; Xiao, H., The Challenge of Applications of Probiotics in Gastrointestinal Diseases. Advanced Gut & Microbiome Research 2023, 2023, 1984200.

21. Gao, J.; Xu, Y.; Zhong, T.; Yu, X.; Wang, L.; Xiao, Y.; Peng, Y.; Sun, Q., A review of food contaminant 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and its toxicity associated with metabolic disorders. Current Research in Food Science 2023, 100617.

22. Li, X.; Zhu, S.; Zhang, X.; Ren, Y.; He, J.; Zhou, J.; Yin, L.; Wang, G.;Zhong, T.; Wang, L.; Xiao, Y.; Zhu, C.; Yin, C.; Yu, X., Advances in the application of recombinase-aided amplification combined with CRISPR-Cas technology in quick detection of pathogenic microbes. Frontiers in Bioengineering and Biotechnology 2023, 11.

23. Liu, Y.; Zhu, L.; Yu, X.; Xu, Y.; Zhong, T., A Combined

Ultrasound–Microwave Assisted Alcoholic–Alkaline Method for Preparation of Granulated Cold-Water-Soluble Starch. Starch - Stärke 2023, n/a (n/a), 2200257.

24. Qiu, J.; Yang, H.; Zhang, Y.; Xiao, Y.; Wang, L.; Peng, Y.; Yu, X.; Huang, X.; Zhong, T., Emerging trends in the application of riboflavin-mediated photodynamic inactivation for food preservation. Trends in Food Science & Technology 2023, 104295.

25. Dong, Y.; Jiang, T.; Wu, T.; Wang, W.; Xie, Z.; Yu, X.; Peng, Y.; Wang, L.; Xiao, Y.; Zhong, T., Enzyme-responsive controlled-release materials for food preservation and crop protection-A review. International Journal of Biological Macromolecules 2023, 128051.

26. Ahmad, T.; Li, G.; Wang, J.; Li, M.; Xiao, Y.; Yu, X.; Zheng, Y.; Moosa, A.; Nie, C.; Liu, Y., First Report of Bacterial Leaf Spot of Ficus benghalensis Caused by Pseudomonas cichorii in Pakistan. Plant Disease 2022, 107 (2), 552.

27. Tao, A.; Zhang, H.; Duan, J.; Xiao, Y.; Liu, Y.; Li, J.; Huang, J.; Zhong, T.; Yu, X., Mechanism and application of fermentation to remove beany flavor from plant-based meat analogs: A mini review. Frontiers in Microbiology 2022, 13.

28. Lu, Y.; Li, Z.; Fan, Y.; Wang, J.; Zhong, T.; Wang, L.; Xiao, Y.; Zhang, D.; Chen, Q.; Yu, X., The Mediating Role of Cumulative Fatigue on the Association between Occupational Stress and Depressive Symptoms: A Cross-Sectional Study among 1327 Chinese Primary Healthcare Professionals. International Journal of Environmental Research and Public Health 2022, 19 (23), 15477.

29. Li, Z.; Li, S.; Xiao, Y.; Zhong, T.; Yu, X.; Wang, L., Nutritional intervention for diabetes mellitus with Alzheimer's disease. Frontiers in Nutrition 2022, 9.

30. Cen, K.; Yu, X.; Gao, C.; Yang, Y.; Tang, X.; Feng, X., Effects of quinoa protein Pickering emulsion on the properties, structure and intermolecular interactions of myofibrillar protein gel. Food Chemistry 2022, 394, 133456.

31. Tao, X.; Shao, Y.; Xu, D.; Huang, Y.; Yu, X.; Zhong, T.; Wang, L.; Chung, S. K.; Chen, D.; Yu, L.; Xiao, Y., Dietary Patterns and Nutrient Intake in University Students of Macao: A Cross-Sectional Study. Nutrients 2022, 14 (17), 3642.

32. Li, X.; Su, L.; Zhang, X.; Chen, Q.; Wang, Y.; Shen, Z.; Zhong, T.; Wang, L.; Xiao, Y.; Feng, X.; Yu, X., Recent Advances on the Function and Purification of Milk Exosomes: A Review. Frontiers in Nutrition 2022, 9.

33. Lin, Y.; Huang, R.; Sun, X.; Yu, X.; Xiao, Y.; Wang, L.; Hu, W.; Zhong, T., The p-Anisaldehyde/β-cyclodextrin inclusion complexes as a sustained release agent: Characterization, storage stability, antibacterial and antioxidant activity. Food Control 2022, 132, 108561.

34. Su, B.; Zhang, Z.; Sun, Z.; Tang, Z.; Xie, X.; Chen, Q.; Cao, H.; Yu, X.; Xu,

Y.; Liu, X.; Hammock, B. D., Fluonanobody-based nanosensor via fluorescence resonance energy transfer for ultrasensitive detection of ochratoxin A. Journal of Hazardous Materials 2022, 422, 126838.

35. Li, X.; Ren, Y.; Liu, D.; Yu, X.; Chen, K., Role of miR-100-5p and CDC25A in breast carcinoma cells. PeerJ 2022, 10, e12263.

36. Yu, X.; Zhong, T.; Zhang, Y.; Zhao, X.; Xiao, Y.; Wang, L.; Liu, X.; Zhang, X., Design, Preparation, and Application of Magnetic Nanoparticles for Food Safety Analysis: A Review of Recent Advances. Journal of Agricultural and Food Chemistry 2022, 70 (1), 46-62.

37. Tao, X.; Chen, D.; Fan, Y.; Zhang, L.; Shan, H.; Wei, Y.; Yu, X.; Zhong, T.; Wang, L.; Chung, S. K.; Yu, Y.; Xiao, Y., A cross-sectional study for the mental health status and sleep quality among college students in Macao during the COVID-19 pandemic. PeerJ 2021, 9, e12520.

38. Cen, K.; Yu, X.; Gao, C.; Feng, X.; Tang, X., Effects of different vegetable oils and ultrasonicated quinoa protein nanoparticles on the rheological properties of Pickering emulsion and freeze-thaw stability of emulsion gels. Journal of Cereal Science 2021, 102, 103350.

39. Ge, Y.; Li, N.; Fu, Y.; Yu, X.; Xiao, Y.; Tang, Z.; Xiao, J.; Wu, J.-L.; Jiang, Z.-H., Deciphering superior quality of Pu-erh tea from thousands of years’ old trees based on the chemical profile. Food Chemistry 2021, 358, 129602.

40. Zhong, T.; Yu, X.; Xiao, Y.; Wang, L.; Tan, L.; Huang, R., Incorporating lipid microparticles into carboxymethyl cellulose films as secondary carriers for stable loading and sustained releasing of carvacrol. Results in Materials 2021, 11, 100205.

41. Huang, S.; Palanisamy, S.; Yu, X.; Wang, Y.; Liu, D.; Gong, W.; Zhang, X., α-Active Pyrylium Salt 2,4,5-Triphenylpyrylium for Improved Mass Spectrometry-Based Detection of Peptides. Analytical Chemistry 2021, 93 (32), 11072-11080.

42. Tao, X.; Chen, D.; Liang, R.; Zhang, X.; Yu, X.; Chung, S.; Yu, Y.; Xiao, Y., A comparative study on knowledge towards COVID-19 prevention among undergraduate students in Macao and Zhuhai, China. PeerJ 2021, 9, e11833.43. Yu, X.; Lee, J. K.; Liu, H.; Yang, H., Synthesis of magnetic nanoparticles to detect Sudan dye adulteration in chilli powders. Food Chemistry 2019, 299, 125144.

44. Yu, X.; Lim, C. Y. X.; Dong, B.; Hadinoto, K., Development of magnetic solid phase extraction platform for the purification of bioactive γ-glutamyl peptides from garlic (Allium sativum). LWT 2020, 127, 109410.

45. Yu, X.; Li, Z.; Zhao, M.; Lau, S. C. S.; Ru Tan, H.; Teh, W. J.; Yang, H.; Zheng, C.; Zhang, Y., Quantification of aflatoxin B1 in vegetable oils using low temperature clean-up followed by immuno-magnetic solid phase extraction. Food Chemistry 2019, 275, 390-396.

46. Zheng, Y.; Yu, X.; Yang, H.; Wang, S., Chapter 5 - From a Perspective of Nutrition: Importance of Organic Foods over Conventional Counterparts. In Safety and Practice for Organic Food, Biswas, D.; Micallef, S. A., Eds. Academic Press: 2019; pp 75-134.

47. Yu, X.; Li, Y.; Ng, M.; Yang, H.; Wang, S., Comparative study of pyrethroids residue in fruit peels and fleshes using polystyrene-coated magnetic nanoparticles based clean-up techniques. Food Control 2018, 85, 300-307.

48. Yu, X.; Ang, H. C.; Yang, H.; Zheng, C.; Zhang, Y., Low temperature cleanup combined with magnetic nanoparticle extraction to determine pyrethroids residue in vegetables oils. Food Control 2017, 74, 112-120.

49. Yu, X.; Yang, H., Pyrethroid residue determination in organic and conventional vegetables using liquid-solid extraction coupled with magnetic solid phase extraction based on polystyrene-coated magnetic nanoparticles. Food Chemistry 2017, 217, 303-310.

50. Yu, X.; Sun, Y.; Jiang, C.-Z.; Gao, Y.; Wang, Y.-P.; Zhang, H.-Q.; Song, D.-Q., Magnetic solid-phase extraction and ultrafast liquid chromatographic detection of Sudan dyes in red wines, juices, and mature vinegars. Journal of Separation Science 2012, 35 (23), 3403-3411.

51. Yu, X.; Sun, Y.; Jiang, C.; Sun, X.; Gao, Y.; Wang, Y.; Zhang, H.; Song, D., Magnetic solid-phase extraction of five pyrethroids from environmental water samples followed by ultrafast liquid chromatography analysis. Talanta 2012, 98, 257-264.

52. Jiang, C.; Sun, Y.; Yu, X.; Zhang, L.; Sun, X.; Gao, Y.; Zhang, H.; Song, D., Removal of sudan dyes from water with C18-functional ultrafine magnetic silica nanoparticles. Talanta 2012, 89, 38-46.

53. Sun, X.-M.; Sun, Y.; Wu, L.-W.; Jiang, C.-Z.; Yu, X.; Gao, Y.; Wang, L.-Y.; Song, D.-Q., Development of a vortex-assisted ionic liquid microextraction method for the determination of aromatic amines in environmental water samples. Analytical Methods 2012, 4 (7), 2074-2080.

54. Jiang, C.; Sun, Y.; Yu, X.; Gao, Y.; Zhang, L.; Wang, Y.; Zhang, H.; Song, D., Liquid–solid extraction coupled with magnetic solid-phase extraction for determination of pyrethroid residues in vegetable samples by ultra fast liquid chromatography. Talanta 2013, 114, 167-175.

55. Gao, Y.; Sun, Y.; Jiang, C.; Yu, X.; Wang, Y.; Zhang, H.; Song, D., Fast Determination of Pyrethroid Pesticides in Tobacco by GC-MS-SIM Coupled with Modified QuEChERS Sample Preparation Procedure. Analytical Sciences 2013, 29 (6), 649-653.

56. Yu, X.; Khani, A.; Ye, X.; Petruzziello, F.; Gao, H.; Zhang, X.; Rainer, G., High-Efficiency Recognition and Identification of Disulfide Bonded Peptides in Rat Neuropeptidome Using Targeted Electron Transfer Dissociation Tandem Mass Spectrometry. Analytical Chemistry 2015, 87 (23), 11646-11651.

57. Wang, Y.; Sun, Y.; Wang, Y.; Jiang, C.; Yu, X.; Gao, Y.; Zhang, H.; Song, D., Determination of Sudan dyes in environmental water by magnetic mesoporous microsphere-based solid phase extraction ultra fast liquid chromatography. Analytical Methods 2013, 5 (6), 1399-1406.

58. Jiang, C.; Sun, Y.; Yu, X.; Gao, Y.; Zhang, L.; Wang, Y.; Zhang, H.; Song, D., Application of C18-functional magnetic nanoparticles for extraction of aromatic amines from human urine. Journal of Chromatography B 2014,947-948, 49-56.

59. Ye, X.; Zhao, N.; Yu, X.; Han, X.; Gao, H.; Zhang, X., Extensive characterization of peptides from Panax ginseng C. A. Meyer using mass spectrometric approach. PROTEOMICS 2016, 16 (21), 2788-2791.

60. Liu, Y.; Zhu, L.; Yu, X.; Xu, Y.; Zhong, T., A Combined Ultrasound–

Microwave Assisted Alcoholic–Alkaline Method for Preparation of Granulated Cold‐Water‐Soluble Starch. Starch‐Stärke 2023, 75 (11-12),

2200257.

61. Jiang, T.; Dong, Y.; Zhu, W.; Wu, T.; Chen, L.; Cao, Y.; Yu, X.; Peng, Y.; Wang, L.; Xiao, Y., Underlying mechanisms and molecular targets of genistein in the management of type 2 Diabetes Mellitus and related Complications. Critical Reviews in Food Science and Nutrition 2023, 1-13.

62. Feng, X.; Yu, X.; Yang, Y.; Tang, X., Improving the freeze-thaw stability of fish myofibrils and myofibrillar protein gels: Current methods and future perspectives. Food Hydrocolloids 2023, 109041.

書籍

1. Safety and Practice for Organic Food, Chapter 5: From a Perspective of Nutrition: Importance of Organic Foods over Conventional Counterparts. Zheng Y; Yu X; Yang H*; Wang S. Elsevier. 2019. ISBN: 978-0-12-812060-6.

專利

1. Novel detection method for Sudan dye pollution in water，Song D，Sun Y，Jiang C，Yu X，Zhang L，Sun X，Gao Y. Patent No.: ZL201110157977.0, Date of Issuance: Nov. 14th, 2012.

專業認證和獎項

“Best Postgraduate Award”, Department of Food Science and Technology, National University of Singapore; “Award of Excellence”, Top 1st of Analytical Chemistry and Energy/Environment Category, Chemistry Graduate Symposium, National University of Singapore; “Honoured Graduate” and National Graduate Scholarship, Jilin U niversity.

專業協會會員資格

Member of editorial board for Advanced Gut & Microbiome Research, Food and Health; Member of youth editorial board for Food Research & Dvelopment; Guest editor for Foods, Frontiers in Nutrtion, Journal of Food Processing and Preservation, Healthcare; Member of Chinese Nutrition Society; Committee member of Students' Affairs Office, MUST