目前，黃博士專注於尋找用於治療癌症、神經退行性疾病、免疫調節，並具有潛在臨床應用價值的天然化合物，同時探究其作用的分子機理。同時，他亦探索醫學人工智能的臨床應用，包括建立人類全週期生物鐘模型，以加深對晝夜節律對疾病與治療影響的理解，並研發用於臨床決策支援的AI工具。透過結合天然產物研究與計算及AI方法，加速從分子水平到臨床落地的轉化。其近期成果發表於Nat. Med., Trends Mol. Med., J. Transl. Med., Chin. Med. J., Pharmacol. Res., Biomark. Res., Food Chem.:X and Int. J. Biol. Macromol.等期刊上。此外，他被任命為澳門特區政府委任為生命科學道德委員會成員，亦曾任人才發展委員會「大健康」產業專責小組成員。
2012年6月：英國謝菲爾德大學醫學博士學位 (Outright Pass)
2007年11月：英國謝菲爾德大學分子醫學(遺傳)碩士學位 (Distinction; Rank: 1st)
2006年7月：北京師範大學生物學學士學位
Biochemistry; HMX programme coordinator; Medical Ethics, Humanities and Law course coordinator; MBBS year 1-5 system block, clerkship coordinator
1. 2025年5月–2028年5月: FDCT, Wong Io Nam (PI), 總狀蕨藻硫酸多糖介導DNA損傷修復途徑提高微衛星穩定型（MSS）胃癌治療效果的機制研究與應用探索, 項目編號 0133/2024/RIA2, MOP$ 1,700,900
2. 2021年9月–2024年9月: FDCT-NSFC, Wong Io Nam (PI), 蕨藻硫酸多糖靶向COX-2介導的鐵死亡重塑免疫代謝的分子機制研究, 項目編號 0069/2021/AFJ, MOP$ 1,600,000
3. 2022年2月–2023年8月: FRG, Wong Io Nam (PI), 利用BioID鄰位生物素標記的方法去探究與SV40宿主抑制因子FAM111A相互作用的潛在新的促病毒和抗病毒因子之特性, 項目編號 FRG-22-022-FMD, MOP $100,000
4. 2024年6月–2027年6月: FDCT-AKP, Paul Kwong-Hang Tam (PI), Chen Yan (Co-PI), Wong Io Nam (Member), 結合再生醫學,多組學及人工智能平台開展改善慢性肝病纖維化的標靶發現及精準干預新診療, 項目編號 0011/2023/AKP, MOP$ 11,917,000
5. 2022年12月–2025年6月: FDCT-ITP, Simon Wing Fai Mok (PI), Wong Io Nam (Co-PI), Vincent Kam Wai Wong (Co-PI), 揭示p53聚合體在類風濕性關節炎病理發展中的調節作用, 項目編號 0037/2022/ITP, MOP $425,000
6. 2022年4月– 2025年4月: FDCT, Olivia Monteiro (PI), Wong Io Nam (Co-PI), Brian Tomlinson (Co-I), Christopher Wai Kei Lam (Co-I), 研究國藥滅活疫苗 BBIBP-CorV 和 BioNTech mRNA 疫苗初種系列及同源與異源加強劑在澳門地區人群中對新冠肺炎病毒株的有效性, 項目編號 0106/2021/A, MOP $644,000
7. 2020年9月–2023年9月: FDCT-NSFC, Zhang Kang (PI), Wong Io Nam (Co-PI), Simon Wing Fai Mok (Co-I), 結膜幹細胞轉化類角膜緣幹細胞與角膜重建, 項目編號0007/2020/AFJ, MOP$ 2,000,000
2019年7月至今：澳門科技大學助理教授
2013年9月–2019年5月：英國牛津大學博士後研究員
2012年5月–2013年9月：英國謝菲爾德大學博士後研究員
2007年2月–2008年8月：英國謝菲爾德大學實驗室技術員
1. Li G, Cheng L, Wong IN*, Yin Y, Chen J, Liu L, Zhang K. Predicting healthspan and disease risks through biological age (2025). Trends Mol Med, DOI: 10.1016/j.molmed.2025.10.006. (*first author, IF 13.8, SCI Q1)
2. Zhong J, Chung SK, Han X, Huang R, Xu B, Wong IN (2025). Front Pharmacol, DOI: 10.3389/fphar.2025.1682025. (Corresponding author, IF 4.8, SCI Q1)
3. Wang K, Liu F, Wu W, Hu H, Shen X, Wang M, Li G, Zeng F, Liu L, Wong IN, Liu S, Zou Z, Li B, Li J, Huang X, Jin S, Li Z, Xu H, Chen G, Chen X, Zhu Y, Li P, Feng Z, Wang W. A full life cycle biological clock based on routine clinical data and its impact in health and diseases (2025). Nat Med, DOI: 10.1038/s41591-025-04006-w. (second author, IF 50.0, SCI Q1)
4. Liu F, Niu Y, Zhang Q, Kang K, Dong Z, Wong IN, Cheng L, Li T, Duan L, Li K, Li G, Hou TW, Fok M, Luo Hu, Chen X, Zhang K, Yin Y. A foundational architecture for AI agents in healthcare (2025). Cell Rep Med, DOI: 10.1016/j.xcrm.2025.102374. (sixth author, IF 10.6, SCI Q1)
5. Huang C, Xiao Y, Xu D, Wong IN, Patil NG, Chen J, Zhang K, Hu W, Zhang J, Ding S, Kuang M, Xiao H, Feng X. Developing a Student-Centred Curriculum: Insights from Anaesthetic Placement Experiences for Co-Designing in China’s Greater Bay Area (2025). Adv medical educ pract., 16, 1695-1704. (second author, IF 1.7, ESCI Q2)
6. Yang L, Mok SWF, Li HH, Wong IN*, Yang LJ. DDX27 in cancer: molecular mechanisms, clinical implications, and therapeutic potential (2025). J Transl Med, 23, 971. (* corresponding author, IF 7.5, SCI Q1)
7. Xia X, Wu Y, Chen Z, Du D, Chen X, Zhang R, Yan J, Wong IN*, Huang R, An edible green algae polysaccharide CRVP from Caulerpa racemosa var. peltate induced apoptosis of liver cancer cells Hepa1-6 by regulating glutathione metabolism (2025). Food Sci Hum Wellness, DOI: 10.26599/FSHW.2024.9250300. (* corresponding author, IF 5.6, SCI Q1)
8. Qu L, Tang Y, Wu J, Yun X, Lo HH, Song L, Wang X, Wang H, Zhang R, Liu M, Wang C, Ng JPL, Fu X, Wong IN*, Wong VKW, Law BYK, FBXL16: a new regulator of neuroinflammation and cognition in Alzheimer’s disease through the ubiquitination-dependent degradation of amyloid precursor protein (2024). Biomark Res., 12, 144. (* corresponding author, IF 9.5, SCI Q1)
9. Wong IN, Monteiro O, Baptista-Hon DT, Wang K, Lu W, Sun Z, Nie S, Yin Y, Leveraging foundation and large language models in medical artificial intelligence (2024). Chin Med J. DOI:10.1097/ CM9.0000000000003302. (first author, IF 7.5, SCI Q1)
10. Zeng J, Liu J, Zhao N, Wong IN*, Huang R, Caulerpa chemnitzia polysaccharide exerts immunomodulatory activity in macrophages by mediating the succinate/PHD2/HIF-1α/IL-1β pathway, (2024). Int J Biol Macromol., 2024 Oct: 134450. (* corresponding author, IF 7.7, SCI Q1)
11. Qin B, Fu S, Xu X, Yang J, Wang Y, Wang L, Huang B, Zhang J, Wu W, Lu H, Law BYK, Wang N, Wong IN*, Wong VKW, Far-infrared radiation and its therapeutic parameters: A superior alternative for future regenerative medicine? (2024). Pharmacol Res., 208 : 107349. (* corresponding author, IF 9.1, SCI Q1)
12. Wang XX, Ji X, Lin J, Wong IN, Lo HH, Wang J, Qu L, Wong VKW, Chung SK, Law BYK, GPCR-mediated natural products and compounds: Potential therapeutic targets for the treatment of neurological diseases (2024). Pharmacol Res., 208: 107395. (second author, IF 9.1, SCI Q1)
13. Zhang J, Tang Y, Feng S, Wong IN*, Guo Y, Zhang J, Chen J, Yang D, Zhang K, Yao W, Li R, Bai Y, Ding S, Kuang M, Xiao H, Xu D, Collaborative Teaching and Curricular Integration in Pre-Intern Clinical Placements: Insights from the Greater Bay Area (2024). Adv medical educ pract., 15, 1027-1037. (* first author, IF 1.8, ESCI Q2)
14. Yu H, Xie Y, Lan L, Ma S, Mok SWF, Wong IN, Wang Y, Zhong G, Yuan L, Zhao H, Macrae VE, He S, Chen G, Zhu D, Sirt7 protects against vascular calcification via modulation of reactive oxygen species and senescence of vascular smooth muscle cells (2024). Free Radic Biol Med., 223: 30-41. (fourth author, IF 7.1, SCI Q1)
15. Xia X, Wu Y, Chen Z, Du D, Chen X, Zhang R, Yan J, Wong IN*, Huang R, Colon cancer inhibitory properties of Caulerpa lentillifera polysaccharide and its molecular mechanisms based on three-dimensional cell culture model (2024). Int J Biol Macromol., 2024 Apr 12:131574. (* corresponding author, IF 7.7, SCI Q1)
16. Yang J, Liu J, Kuang W, Lin Y, Zhong S, Kraithong S, Zhang X, Wong IN*, Huang R. Structural characterization and ferroptosis-related immunomodulatory of a novel exopolysaccharide isolated from marine fungus Aspergillus medius (2024). Int J Biol Macromol., 2024 Mar 6:130703. (* corresponding author, IF 7.7, SCI Q1)
17. Wijesekara T, Huang R, Wong IN*, Xu B, Insights into immunoregulatory effects of bioactive polysaccharides derived from seaweeds through gut microbiota (2024). Food Biosci., 58: 103800. (* corresponding author, IF 4.8, SCI Q1)
18. Wang HM, Lai HJ, Wu AG, Tong Y, Song LL, Lo HH, Wong IN, Wong VKW, Law BYK. Melanogenic effects of 5-demethylnobiletin on mouse model of chemical-induced vitiligo (2024). J. Funct. Foods, 112: 105962. (seventh author, IF 3.8, SCI Q2)
19. Zeng J, Lin Q, Xu J, Xu B, Wong IN*, Huang R, Oligosaccharides Preparation from Caulerpa racemosa var peltate with Enzymatic Hydrolysis and Its Mechanism of Immunomodulatory Activity (2024).食品科學. (* corresponding author, IF 2.1, CSCD)
20. Qiu C, Chan JTW, Zhang DW, Wong IN, Zeng Y, Law BYK, Mok SWF, Dias IRDSR, Liu W, Liu L, Wong VKW. The potential development of drug-resistance in rheumatoid arthritis patients identified with p53 mutations (2023). Genes Dis., 10(6):2252-2255. (second author, IF 6.9, SCI Q1)
21. Tam HH, Zhu D, Ho SSK, Vong HW, Wong VKW, Mok SWF, Wong IN. Potential enhancement of post-stroke angiogenic response by targeting the oligomeric aggregation of p53 protein (2023). Front. Cell. Neurosci., 17:1193362. (corresponding author, IF 4.2, SCI Q2)
22. Wu Y, Liu J, Hao H, Hu L, Zhang X, Luo L, Zeng J, Zhang W, Wong IN, Huang R. A new polysaccharide from Caulerpa chemnitzia induces molecular shifts of immunomodulation on macrophages RAW264.7 (2022). Food Chem.:X, 14: 100313. (eighth author, IF 6.5, SCI Q2)
23. Yang L, Liu J, Xia X, Wong IN, Chung SK, EI-Seedi HR, Wang B, Hunag R. Sulfated heteropolysaccharides from Undaria pinnatifida: Structural characterization and transcript-metabolite profiling of immunostimulatory effects on RAW264. 7 cells (2022). Food Chem.: X, 13:100264. (third author, IF 6.5, SCI Q1)
24. Xia X, Hao H, Zhang X, Wong IN, Chung SK, Chen Z, Xu B, Huang R. Immunomodulatory sulfated polysaccharides from Caulerpa racemosa var. peltata induces metabolic shifts in NF-κB signaling pathway in RAW 264.7 macrophages (2021). Int J Biol Macromol., 182:321-332. (third author, IF 7.7, SCI Q1)
25. Monteiro O, Bhaskar A, Wong IN, Ng AKM, Baptista-Hon DT. Teaching bioelectricity and neurophysiology to medical students using LabAXON simulations (2021). Adv Physiol Educ., 45(4):702-708. (third author, IF 1.7, SCI Q2)
26. Wong IN, Neo JPS, Oehler J, Schafhauser S, Osman F, Carr SB, Whitby MC (2019). The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast. eLife, 8, e49784. (first author, IF 6.4, SCI Q1)
27. Morrow CA, Nguyen MO, Fower A, Wong IN, Osman F, Bryer C, Whity MC (2017). Inter-fork strand annealing causes genomic deletions during the termination of DNA replication. eLife, 6, e25490. (fourth author, IF 6.4, SCI Q1)
28. Wong IN, Sayers JR, Sanders CM (2016). Bacteriophage T5 gene D10 encodes a branch-migration protein. Scientific Reports, 6, 39414. (first author, IF 3.8, SCI Q1)
29. Wong IN, Sayers JR, Sanders CM (2013). Characterization of an unusual bipolar helicase encoded by bacteriophage T5. Nucleic Acids Res, 41(8), 4587-600. (first author, IF 16.7, SCI Q1)
黃耀南，鐘靜，黃日明，鐘金淑子；一種多糖的新用途。申請號: CN202510042159.8
2008年–2012年：英國謝菲爾德大學博士獎學金
2006年–2007年：澳門高等教育局研究生獎學金
2002年–2006年：澳門教育暨青年局大專獎學金
2002年：澳門蓮花獎
1999年：澳門總督獎
2025年2月至今：澳門特區政府生命科學道德委員會成員
2023年7月–2025年6月：澳門特區政府人才發展委員會大健康產業專責小組成員
2025年3月至今：澳門科技大學醫學倫理委員會成員
2024年8月至今：澳門科技大學臨床倫理委員會成員
2019年8月至今：澳門科技大學學術誠信委員會成員
2019年8月至今：澳門科技大學學生紀律獎懲委員會委員
2019年7月–2020年8月：澳門科技大學醫藥綜合教學實驗管理委員會委員
